Continuous outcomes were analyzed using ANCOVA, with randomized treatment as a factor and baseline body weight as a covariate, while categorical data were analyzed with binary logistic regression
Phagoora J, Saini S, Raghunathan A, Reji J, Shabir A, Wanis M, Dejesus D
Exogenous AAS inhibit endogenous testosterone production, and discontinuation of their use is often associated with a prolonged decrease in testosterone secretion ( The substances used in PCT are administered in the treatment of male hypogonadism unrelated to androgen abuse ( To restore endogenous testosterone, mainly aromatase inhibitors (AIs), selective estrogen receptor modulators (SERMs), and human chorionic gonadotropin (hCG) are used ( In the 2024 WADA Prohibited List ( Aromatase is an enzyme that converts testosterone to estradiol (the most potent estrogen form) and androstenedione to estrone ( The anti-estrogenic compounds mentioned in the WADA list can be divided into two groups: SERMs (bazedoxifene, clomiphene, cyclofenil, ospemifene, raloxifene, tamoxifen, and toremifene) and selective estrogen receptor degraders (SERDs), of which fulvestrant is a representative
However, many patients can begin injections right away if theyre showing symptoms of deficiency, as B12 is very safe
10.1186/s12951-020-00668-5 128 WangX.YaoM.MaL.YuP.LuT.ZhangL.et al (2021)
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