The results were highly instructive: At the 100 ng/mL threshold zero non-smoker positives At the 75 ng/mL threshold zero non-smoker positives At the 50 ng/mL threshold (the DOT initial screening standard) only a single positive occurred, even in a sealed unventilated room with heavy smoke At a 20 ng/mL threshold multiple positives occurred Maximum THC metabolite concentrations for non-smokers by GC-MS ranged from 1.3 to 57.5 ng/mL under extreme unventilated conditions The key takeaway: for someone who does not smoke to fail a drug test due to secondhand smoke, they would need to be exposed to a high concentration of smoke in an unventilated space for a prolonged period
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Smokers are more likely to develop these problems than non-smokers
After activation, the released fill saturates the surrounding fibres, which can temporarily alter draw resistance
PKC activation reduces amiloride-sensitive epithelial sodium channel (ENaC) expression, which is important for alveolar fluid clearance (AFC) and results in enhanced lung edema and worsened lung function [47]
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