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[3, 4] Neurons afflicted with Lewy formations remain viable for a relatively long period, but are functionally compromised and die prematurely

Our immune system relies on chemical messengers known as cytokines to work properly

Int J Radiat Oncol Biol Phys (2014) 90(5):110818

Formula: dose in mg concentration in mg/mL = mL

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ICIs work by blocking the interactions between immune checkpoints such as CTL-associated protein 4 (CTLA-4), programmed cell death-1 (PD-1), and programmed cell death ligand-1 (PD-L1) and their ligands, which releases the inhibitory brakes of T cells and results in the robust activation of immune responses (Fig