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High levels of nicotine (1M and above) increase the risk of infectious and autoimmune diseases

10.1158/1055-9965.EPI-04-0498 29 HatsukamiD

California raised the minimum legal age to purchase, use, or possess tobacco or cannabis products, which includes vapes, to 21 years in 2016

Illegal Sales The WHO (2015) estimates that 600 billion cigarettes, or more than 10% of all cigarettes consumed globally, are sold on the illicit market each year

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