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When alcohol is consumed in the presence of naltrexone, it produces significantly less reward, reducing the craving reinforcement cycle over time

Huang T, Gu J, Zhang K, Sun L, Xue X, Zhang C, et al

The patient was reduced to social withdrawal, infrequent smiles, and little intelligible speech

[1] Additionally, the authors indicate that there is still a requirement for successful human trials to be completed prior to clinical translation as there are important differences between rodent and human physiology that could have a significant impact on the efficacy and safety of any agent

doi: 10.1016/j.bbamcr.2019.06.004 26

A peptide cant outwork a blocked airway or a stimulant taken too late