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Between 2013 and 2020, the total direct cost attributable to smoked tobacco use among males and females for current health expenditure was $9.37 billion, and $749.66 million for smokeless tobacco
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Tobacco production involves application of a range of chemicals at different stages in the growth process, and several pesticides commonly used during tobacco farming are known neurotoxins
Comparing the effect of mainstream and sidestream smoke on mouse male germ cells, Polyzos et al [33] showed that sidestream smoke reduced sperm motility, whereas mainstream smoke increased sperm DNA fragmentation
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