The dermis was replaced by scar connective tissue with a chaotic arrangement of thick fibers and large cavities with a transparent content and a small amount of blood vessels, around which were noted perivascular edema and leukocytic infiltration with a predominance of macro- phages
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I grew up in the sixties where taking the bus to school in the morning meant sitting on a fume filled top deck surrounded by adults puffing on their Park Drives and Players Number 6