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Patients should be reviewed 812 weeks after commencing treatment to assess: Symptomatic improvement, particularly resolution of fatigue and neurological symptoms Haematological response (normalisation of haemoglobin and mean cell volume) Reticulocyte count typically rises within one week, indicating bone marrow response Repeat serum B12 testing is generally not useful after starting parenteral therapy, as levels remain elevated for months

The problem is that many critical peptide levels decline as you age

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In addition to stimulating GLP-1 receptors, it also activates glucose-dependent insulinotropic polypeptide (GIP) receptors, which are involved in both insulin signaling and lipid metabolism (Nauck & DAlessio)

Taking creatine with meals may improve tolerance and absorption