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CS exposure in humans involves complex variables such as inhalation dynamics, metabolic processing and tissue clearance that are difficult to replicate in cell culture systems

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Discussion The estimate of the effect of exposure to spousal smoking is based on current (2008) data on the proportion of persons married or cohabiting, and an estimate of the likelihood that their current partner has ever smoked

171 More well-designed smoking cessation studies need to be conducted with adolescent smokers, particularly in the area of pharmacologic treatments for nicotine dependence

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