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If you have any infection-related symptoms, such as fever, chills, or obvious redness and swelling at the incision site, you should get in touch with your doctor

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Among the most frequently identified are infection, significant exposure to sunlight or cold, stress, fatigue, local trauma (dental procedures, cracked skin), or a reduction in immune defenses (illness, corticosteroid or immunosuppressant use)

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Pharmacol Biochem Behav 78 : 581592