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[128] also commented on the fact that normalizing toxin production in smoke gave a misleading picture of the effects of the additives on smoke toxicity

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For example, high levels of cotinine suggest regular heavy smoking, while low levels may indicate intermittent use or second-hand exposure

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Only those who responded positively to the latter question (that they had ever heard about E-cigarettes) were asked about their knowledge and beliefs and their source(s) of information about E-cigarettes