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George Michael, almost uniquely, travelled in exactly the opposite direction

The National Institute on Drug Abuse of the National Institutes of Health and the Center for Tobacco Products of the US Food and Drug Administration helped support this work, but the authors' views do not necessarily represent those of the NIH, FDA or Pennsylvania Department of Health

Reference: Antonello G, Blostein F, Bhaumik D, et al

Tobacco and cannabis use patterns are also evolving, and many teens are combining the two products

When mitochondrial damage exceeds the clearance capacity of the quality control mechanisms, a disordered state that fails to effectively deal with mitochondrial dysfunction ensues, further exacerbating functional abnormalities and creating a vicious cycle that may contribute to COPD progression