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You only need a little bit of exposure to give you the big harmful effects

[202] The strategy's opponents labeled it "McCain's plan" [203] and University of Virginia political science professor Larry Sabato said, "McCain owns Iraq just as much as Bush does now." [178] The surge and the war were unpopular during most of the year, even within the Republican Party, [204] as McCain's presidential campaign was underway

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Beyond these changes in gene expression, smoking also induced changes in methylation patterns