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Patients should be reassured about the safety, efficacy and low addictive potential of NRT, as misinformed concerns are a major cause of poor adherence

[9] The World Health Organization estimates that, annually, more than 7 million people die from tobacco-related causes, including 1 } : CS1 maint: DOI inactive as of July 2026 (link) Endocrine

It is well known that the most addictive ingredient of tobacco is nicotine, but keep in mind that tobacco also contains addictive caffeine and that one cigarette can release as many as 7,000 other chemicals

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