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[78] However, as the plastic polymer networks degrade, biocide previously within the polymeric "mesh" leaches into the ocean

The new chemicals derived from benzaldehyde and cinnamaldehyde were more toxic than the vanillin-derived compounds. The new chemicals also activated sensory irritant receptors in nerve endings in the bronchi called TRPV1 and TRPA1, which are responsible for a range of inflammatory responses

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This is due to both the repetitive motion of smoking and the breakdown of skins support structures

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