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A recent study found adolescent e-cigarette smokers urine tested positive for at least five of the same cancer-causing chemicals found in traditional cigarettes and since anyone who smokes an e-cigarette is inhaling nicotine in varying degrees, there should be caution about its use

Nicotine Dependence, Depression, and Gender: Characterizing Phenotypes Based on Withdrawal Discomfort, Response to Smoking, and Ability to Abstain

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I would also share that the age of onset (first use), frequency, and intensity (potency) are also very important considerations when thinking about using a substance