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And Paley, to his credit, did everything he could to try and make it work

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Further, a critical limitation of most traditional in vitro existing smoke models is their reliance on the use of cigarette smoke extract (CSE) rather than whole cigarette smoke (CS)

"It looks like addiction is not just about the substance itself, but also the belief you need the substance to have a normal daily life," Gu said

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Metal was a popular choice because of its durability, its appearance, which could be heavily ornamented or decorated, and because it was a status symbol