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While our study did not differentiate between methods of cannabis consumption, cannabis is most commonly consumed by smoking, Kokot said in an email

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2) directly, since the lung possesses an extremely large surface area for gas exchange, it is possible that gas-phase cigarette smoke components interact with plasma constituents in the interstitial fluid

They mimic vital endogenous cannabinoids already present in our body and are a helpful substitute if we are low on these

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