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Celli A et al (2022) Lifestyle intervention strategy to treat diabetes in older adults: a randomized controlled trial
In January 2025, the FDA authorized 20 ZYN nicotine pouch products after years of scientific review, finding that their benefits to public health outweigh the risks.[2] The agency determined that the pouches contain substantially fewer harmful chemicals than cigarettes and that a significant share of adult smokers who used them switched away from combustible tobacco (like cigarettes and cigars) entirely
At the same time, we found no significant differences between their smoke- and air-exposed samples for the metabolic pathway of fatty acid degradation, while for the other outcomes, there is no supporting evidence