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Consumer-facing claims about BPC-157 efficacy in humans for tendinopathy, joint pain, gastrointestinal disorders, or neurological conditions therefore extrapolate from rat and HUVEC work and are not supported by controlled human evidence

Still, more research is needed

For serious research, a dedicated lab refrigerator is always the superior choice

No tolerance development to the lipolytic effects was noted in these studies, suggesting that unlike beta-2 agonists (which rapidly desensitize their receptors), beta-3 receptor activation may not produce the same downregulation pattern

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Despite these improvements, Roche decided to discontinue research into acmopatide and abandon plans for a phase 3 clinical trial