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To obtain a two-tailed p -value of 0.05 and a difference between the exposed and control groups that corresponds to a 25% higher mean level of MN among the exposed, a minimum of 49 subjects would be needed in each group

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You can drink plenty of water and exercise

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Reynolds American has agreed to be fully acquired by British American Tobacco, the cigarette companies said on Tuesday, in a $49 billion deal that will create a global tobacco powerhouse

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