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The ISO method that is currently used to determine TNCO values underestimates the quantity of harmful substances to which smokers are exposed

5 In the UK, smoking is the leading risk factor for early death, ahead of obesity, high blood pressure, cholesterol, and other behavioral and environmental factors

The designs varied widely on these

It may be more relevant to other countries, where unfiltered tobacco products are more common, Glantz adds

the inclusion of data from 6 countries meant that it was not possible to include researchers who were embedded within the various specific cultural contexts

doi:10.1016/j.chemosphere.2020.128731