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"This sad mood makes it hard for people to quit, especially in the first few days," said Jeffrey Meyer, the lead researcher and a senior scientist at the Centre for Addiction and Mental Health in Toronto

Sometimes artists scrap projects and spit out their seminal masterpieces in a matter of weeks

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It's important to remember that the benefits of prescribed medications often outweigh temporary side effects

Outcome measures Primary outcome The abstinence rate for smoking cessation at week 24 (number of people who quit smoking/total number of people) will be considered the primary outcome