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High doses of PCP can cause seizures, coma, and even death (often as a consequence of accidental injury or suicide while under the drug's effects)

M., Cremers, H

As of February 18, 2020, there have been 2,807 reported cases and 68 deaths related to EVALI

Environ Pollut 238:972976 Seshacharyulu P, Ponnusamy MP, Haridas D, Jain M, Ganti AK, Batra SK (2012) Targeting the EGFR signaling pathway in cancer therapy

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It is a bit pricier than some of the other lighters on this list, though its build quality easily justify its MSRP and then some