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130 Comparatively, the deficiency of ZIP8 has a substantial impact on zinc influx in effector T cells and results in reduced TCR-mediated signaling, including NF-B and MAPK signaling, which are involved in the differentiation of T helper (Th)17 cells

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tuberculosis infection TB (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations