A cluster of at least three of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoprotein (HDL) levels
Similarly, TGR5 activation elevates intracellular cAMP levels, leading to downstream activation of protein kinase A (PKA) and exchange protein directly activated by cAMP (Epac), which suppresses NF-B signaling, inhibits NLRP3 inflammasome activation, and can promote macrophage polarization from the pro-inflammatory M1 phenotype toward the anti-inflammatory M2 phenotype 148
Retinol: GHK-Cu can be used with Retinol, and many find they work synergistically
Anti-Inflammatory Support Both compounds are believed to blunt inflammation, which could ease chronic soreness, joint stiffness, or flare-ups from overtraining
It works by signaling your DNA to produce more collagen and elastin while also acting as a powerful protector against inflammation and aging
This stack accelerates cellular repair and works synergistically with our Regenerative Medicine and Bio-Identical TRT protocols