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Oxidative stress is a transient or long-term increase of the steady-state level of reactive oxygen species (ROS) leading to oxidative modifications of biomolecules and cell death via necrosis or apoptosis (Lushchak, 2014

Related to physiology, GSH is imported and degraded as a sulfur source in Francisella species 20,21,22 , while Streptococcus species and Hemophilus influenzae rely on host GSH to defend against oxidative stress 23,24