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As mentioned before, free radicals have been found to react with macromolecules (lipids, proteins, DNA) within the cell, with one of the most frequent targets being the polyunsaturated fatty acids that largely comprise the cell membranes

While results in experimental models are promising, research remains preliminary, and findings are not yet conclusive for translational outcomes

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While current evidence suggests no significant increase in these risks, ongoing research is needed to understand better the long-term safety and efficacy of these medications in diverse patient populations

Sumaryada, T., Nabilah, F., Handayasari, F., Kartono, A