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Additionally, one clinical study reported that consumption of chlorogenic acid-enriched coffee not only improved plasma antioxidant capacity and decreased plasma lipid and protein oxidation but also donated to enhancing cardiovascular health in people with hypercholesterolemia [169]

Given the limited evidence base, patients should weigh the financial commitment against the uncertain benefits and prioritise proven interventions first

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Like other enzymes that transfer two-carbon groups, transketolase requires thiamine pyrophosphate (TPP) as a co-factor in the transfer reaction

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