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These effects mean GHK-CU should, theoretically, calm irritated skin rather than worsen it

2006 Apr;97(2):303-9

Collagen Production Several studies referenced by the review article showed GHK-Cu increased collagen synthesis and glycosaminoglycan production

Regular use and maintenance are required to sustain any lightening effects, and results can vary among individuals

At baseline and at 2-, 4-, 6-, and 8 weeks, skin hydration (by a skin capacitance meter) and skin elasticity (by a cutometer) were quantified

Manufacturer labels often list 28 days, but real-world community use shows the peptide and the preservative both hold up well past that with clean handling and proper storage