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Homozygous HbC disease (HbCC) results in mild chronic haemolytic anaemia with splenomegaly

All participants were instructed to follow a diet with a 300 kcal deficit and to increase their physical activity gradually to 30-60 minutes of exercise per day

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FAK (focal adhesion kinase) and paxillin are proteins that regulate how cells attach and move a crucial factor in tissue repair

Magnesium contributes to normal energy-yielding metabolism

The funding bodies were not involved in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript