however, neither dataset showed detectable expression of Mtnr1a or Mtnr1b in these cells ( Supplementary Figure 3C )
Single-cell gene expression analysis from a publicly available database [18] suggested dysregulation of both GPX4 as well as iron handling in proximal tubular epithelial cells of the S3 segments, which are known to be the most ferroptosis-prone part of the nephron[24] (Fig
The main results you can expect include: 1
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While numerous studies have demonstrated encouraging preclinical outcomes using polyphenols such as curcumin, quercetin, resveratrol, and betulin encapsulated in lipid- or polymer-based nanocarriers, their translational promise remains highly variable