PMID: 30074168
Side effects were mostly gastrointestinal, including nausea, vomiting, diarrhea and constipation, which are all commonly reported adverse events for approved weight loss drugs
Retatrutide an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously represents the cutting edge of obesity biology research as of 2026
Alternative approach: Focus on nutrition (AREDS2 safe in pregnancy, omega-3s beneficial), conventional treatments if needed, defer peptide experimentation until after breastfeeding
Inject Monday through Friday, rest on weekends
Unlike acetaminophen, ibuprofen is an anti-inflammatory pain killer, which means that it will really help the swelling or inflammation go down