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Semax, as noted above, contains an ACTH(47) fragment flanked at the C-terminus by the PGP tripeptide

TaipalensuuJ.TornblomH.LindbergG.EinarssonC.SjoqvistF.MelhusH.GarbergP.SjostromB.LundgrenB.ArturssonP.2001Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.2991164170

A comprehensive review of conventional and stimuli-responsive delivery systems for bioactive peptides: from food to biomedical applications

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Herniated tissue can impinge on spinal nerves and cause distressing symptoms (sciatica) radiating to the buttock or leg