Extracellular matrix and collagen research Beyond the wound-healing context, GHK-Cu is used in research on extracellular matrix biology more generally including collagen synthesis, the cross-linking reactions catalyzed by lysyl oxidase, the deposition and remodeling of matrix in various cell-culture systems, and the broader matrix metabolism that connects to tissue mechanics and tissue function
Research published in peptide patent literature from Diagen indicates the arginate form can achieve oral bioavailability exceeding 90%, compared to less than 3% for the acetate form
This makes oral supplementation of glutathione an appealing option
10.1007/s10787-017-0358-8 [DOI] [PubMed] [Google Scholar] Berkopic Cesar L., Gojkovic S., Krezic I., Malekinusic D., Zizek H., Batelja Vuletic L., et al
It is also fortified in nutritional yeast products and some breakfast cereals
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