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As this study comprehensively evaluated how microbes and their derived metabolites alter gut physiology by direct CNS-mediated gut sympathetic modulation, separate research implicates the role of the aryl hydrocarbon receptor (AHR) as a critical node in regulating gut physiology and neurogenesis (Obata et al., 2020

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Additionally, subgroup analyses showed higher response rates in glycopyrrolate/eFlow CS 25mcg (i.e., the approved dose) as compared with placebo among all subgroups by age, FEV 1 % predicted, PIFR, or background LABA use at baseline

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