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The combination of autophagosome isolation and quantitative proteomics has identified nuclear receptor coactivator 4 (NCOA4) as the cargo receptor responsible for autophagy-dependent ferritin degradation (52)

(PubMed) National Institute of Diabetes and Digestive and Kidney Diseases

Khanna N, Nazli T, Siddiqui KM, Kalaivani M

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Improves glucose regulation: Slowing digestion also smooths out post-meal blood sugar spikes, helping stabilize energy and metabolic health

This can lead to: Greater risk of hypoglycemia , especially when fasted Long-term insulin resistance if misused Higher chance of receptor desensitization However, it has fewer injection site issues , as its typically administered subcutaneously or intramuscularly away from the training site