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But in a secondary analysis of this study, patients were grouped according to inflammatory degrees, and the therapeutic effect of simvastatin on the hyperinflammatory phenotype was observed (27)

Hence there were two main goals of this study

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The dosing ranges referenced are derived from preclinical research models and observational, non-clinical protocols

This connects the oxylipin 13-HODE with the enhanced cytotoxicity induced by albumin