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The gut microbiome connection was apparent almost 30 years in research and in a clinical setting, which led to the creation of an antibiotic named Virginiamycin in the 1990s

Different clinical syndromes associated with the deficiency of this enzyme have been described and they include: Hemolysis induced by drugs

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Administering these compounds has been shown to effectively mitigate memory deficits and markedly reduce the expression of phosphorylated tau in the hippocampus in the APP/PS1 double-transgenic mice

Finally, several peptides from the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) were consistently enriched with pathology

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