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Furthermore, although the applicant states that HP [129] Xe MRI can be used to quantify abnormalities across three compartments of alveolar gas-exchange (in the airspaces (ventilation), barrier tissue of the lung parenchyma, and transfer to red blood cells (RBCs)), we question whether the detection of such abnormalities allows for a specific diagnosis of disease

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J Neurol Neurosurg Psychiatry 1999;66:177183

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