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This reaction is essential in lipid-rich environments, such as cellular membranes, where lipid peroxidation can lead to cell death

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In some embodiments, the otic formulation or composition comprises between about 0.001% to about 2% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

It regenerates other oxidized antioxidants like vitamin C and vitamin E, is involved in the repair of peroxidized lipids and in the maintenance of sulfhydryl moieties of proteins in the reduced form

Epub 2017 Jan 11

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