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Glutathione is a naturally occurring intracellular antioxidant, and tirzepatide is a GIP/GLP-1 dual agonist that works through incretin receptor signalling

In line with the biphasic kinetic profile of dexamethasone-mediated ferroptosis modulation, increased accumulation of the non-enzymatic lipoxid protein modification 4-HNE upon erastin treatment was observed (Supplementary Fig

Ultimately, activation of matrix metalloproteinases degrades collagen matrices and promotes smooth muscle cell apoptosis, leading to plaque destabilization [322]

The authors concluded that high-dose curcumin supplementation effectively reduces oxidative stress and inflammation in postmenopausal women [64]