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Due to their high reactivity, ROS typically oxidize targets with or adjacent to the intracellular compartment where they are produced, affecting surrounding neighboring cells

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Only after parents agreed to enroll their children in the study and signed informed consent, a detailed medical history, current drug/supplement intake, and some demographic information about the child and parents were collected

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So when this metabolite and its mitochondrial transporter showed up in cancer screenings, Birsoy knew where to take his experiments next

Zhang, L., Sun, A., Li, A., Kang, J., Wang, Y., & Liu, R