Regarding chronic exposure, cases of cardiac fibrosis [91], increased cardiac inflammation [92], and enlarged left ventricle [84] have been identified in preclinical models exposed to e-cigarette aerosol for three to eight months
Scientists do not yet know whether a person using nicotine (by itself) for many years will develop cancer or heart disease, because people have not been using nicotine-only products for long enough (for example, 30 years) to do the studies
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J Inflamm Res
