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In general, older adults often need lower doses of CNS-active compounds due to changes in metabolism, body composition, and tissue sensitivity

Copper concentrations do not usually exceed 3500 g/g dry weight

People who had recently taken antibiotics were low converters (as were people who had mechanical bowel cleansing, which doesnt sound pleasant).[ref] The absorption of sulforaphane (glucosinolates already converted by myrosinase) is fairly high in the 70-90% range

AbdallahCGHannestadJMasonGFHolmesSEDellaGioiaNSanacoraGet al

Two people can take the same dose of tirzepatide and have vastly different outcomes based on genetics, starting body composition, activity level, diet quality, sleep patterns, stress levels, and dozens of other variables

The WNT protein family consists of glycoproteins that are secreted and bind to Frizzled receptor (FZD) proteins, which have seven transmembrane segments