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Imatinib works by blocking an abnormal BCR-ABL protein (that forms as the result of a cancerous mutation) which signals leukemia cells to divide uncontrollably

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Given that the elevated ILC3 frequencies in smokers with asthma correlated positively with not only smoking amount and decreased lung function but also M1 macrophage and circulating neutrophil frequencies, it may be the key player in the pathogenesis of smoking-related asthma is the ILC3s

Respir Res 17 , 57 (2016)

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