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Hall S, McDermott C, Anoopkumar-Dukie S, et al

Finally, given the pragmatic nature of the proposed trial, the decision was taken to include consecutive patients seeking medical help at the participating centres, thus ensuring the enrolment of subjects similar to those that would be seen in normal clinical practice

Protein hydropersulfidation may also contribute to cytoprotection because it can be expected to protect protein thiols against irreversible oxidation: while unprotected protein thiols can form irreversibly oxidized products (sulfinic and sulfonic acids), the corresponding protein persulfide oxidation products (perthiosulfinic and perthiosulfonic acid) can still be reduced to regenerate the unmodified thiol (Millikin et al., 2016

These conditional effects on several systems throughout the body are one therapeutic application of DSIP

In laboratory environments, researchers often utilize bacteriostatic water during peptide handling and reconstitution procedures involving lyophilized compounds

Thus, results can vary