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Most people who experience side effects report feeling bloated or a bit nauseous, and this typically happens during a loading phase (where one takes 20-25 grams of creatine for 5-7 days to achieve muscle saturation more quickly), which is unnecessary

A 2018 article published in Nutrients also states that in vitro and in vivo studies have determined that glutamine is an essential nutrient for lymphocyte proliferation and cytokine production, macrophage phagocytic plus secretory activities, and neutrophil bacterial killing. In fact, glutamine is currently part of clinical nutrition supplementation recommended for immune-suppressed individuals