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Insulin Resistance and Outcomes in Surgery

Acetylcysteine may be introduced directly into a particular segment of the bronchopulmonary tree by inserting (under local anesthesia and direct vision) a small plastic catheter into the trachea

Structurally, downregulation of key tight junction proteins (e.g., occludin, claudins) together with upregulation of pore-forming proteins (e.g., claudin-2) directly weakens the physical barrier (Zeng et al., 2024)