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While brain interstitial fluid tau concentrations are reported to be nearly twice as high during the active period of the rest-activity cycle in humans [8], it is noteworthy that, to the best of our knowledge, no study has investigated whether the deletion of core clock genes, simulating circadian disruption, leads to an increase in tau hyperphosphorylation

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This protective effect helps maintain optimal brain function and reduces the risk of cognitive decline

For MS-DRG 253, we identified a total of 16,650 cases with an average length of stay of 5.2 days and average costs of $22,685

Tadela Susmitha : Validated analyses, assisted in manuscript refinement, and ensured quality control